In which patient population is the use of antivirals like Gancyclovir particularly risky?

The use of antivirals like Ganciclovir is particularly risky in immunocompromised patients due to their weakened immune systems. These individuals are more susceptible to infections and may require antiviral treatment; however, their compromised state can also lead to an increased risk of adverse effects from these medications. Ganciclovir is known to cause significant myelosuppression, which can further exacerbate the patient's already vulnerable condition by increasing the risk of infections, anemia, or bleeding due to lowered blood cell counts. Additionally, Ganciclovir requires careful monitoring of renal function and potential drug interactions, making its use in this population even more complex and potentially dangerous.

In contrast, children with mild infections, older adults without comorbidities, and patients with mild acute illnesses generally have stronger immune responses, allowing for a safer therapeutic approach to antiviral treatments.