Nucleoside analogs like Tenofovir are primarily used in the treatment of which virus?

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Nucleoside analogs, such as Tenofovir, are primarily utilized in the treatment of Human Immunodeficiency Virus (HIV) and Hepatitis B due to their mechanism of action, which involves mimicking the building blocks of nucleic acids. By substituting for natural nucleotides, these analogs effectively interfere with the viral replication processes. In the case of HIV, Tenofovir acts as a reverse transcriptase inhibitor, preventing the virus from converting its RNA into DNA, a critical step in the viral lifecycle. Similarly, it is beneficial in managing Hepatitis B by inhibiting viral DNA synthesis.

Other viruses listed in the choices do not primarily use nucleoside analogs like Tenofovir in their treatment protocols. For instance, while Herpes Simplex Virus management relies on other antiviral agents like acyclovir, nor does it involve Tenofovir, which is more specific to HIV and Hepatitis B. Similarly, Influenza virus treatments do not typically include nucleoside analogs, instead they often utilize neuraminidase inhibitors such as oseltamivir. Hepatitis C treatments have shifted towards direct-acting antivirals that target specific proteins essential for viral replication rather than nucleoside analogs. Thus,

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