What are the common side effects of interferon therapy?

Interferon therapy, commonly used in the treatment of viral infections and certain cancers, is known for its range of side effects. Among these, flu-like symptoms are the most frequently reported. These symptoms can include fever, chills, fatigue, and general malaise, which are reminiscent of the body’s response to an infection. Such reactions are a result of the immune system being stimulated by the interferon, as it works to enhance the immune response against viruses or malignant cells.

While respiratory issues, gastrointestinal disturbances, and dermatological reactions can occur with interferon therapy, they are not as universally associated with it as flu-like symptoms. The prominence of flu-like symptoms in patients receiving this therapy is significant enough that many healthcare providers preemptively treat patients with analgesics or antipyretics to help alleviate these effects. Understanding this common adverse reaction helps clinicians manage patient expectations and provide supportive care throughout the treatment process.