What is a potential risk associated with using antivirals?

The development of drug resistance is a significant concern when using antiviral agents. This risk arises when viruses undergo mutations that allow them to survive despite the presence of antiviral drugs designed to inhibit their replication or function. Over time, this can lead to a population of viruses that is no longer affected by the antiviral treatment, making it less effective in managing infections.

When antiviral treatments are used, particularly if they are not taken consistently or as directed, the pressure applied on viral populations can enable the most resilient variants to thrive. This phenomenon is similar to what is observed in bacterial infections with antibiotics, where incomplete courses of treatment can lead to resistant strains. Thus, the emergence of drug-resistant viruses can severely limit treatment options and complicate patient management.

In contrast, options such as enhanced drug metabolism, increased susceptibility to infections, and reversal of disease progression are less associated with antiviral use. Enhanced drug metabolism refers to the body breaking down drugs more quickly, which is more of a pharmacokinetic concern rather than a direct consequence of antiviral therapy. Increased susceptibility to infections might occur due to underlying factors unrelated to antiviral use. Lastly, reversal of disease progression is typically a desired outcome of antiviral therapy rather than a risk associated with it.