Which drug is primarily excreted in feces and suitable for clients with renal impairment?

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Nelfinavir is primarily excreted in feces and is generally considered suitable for clients with renal impairment. This characteristic makes it particularly beneficial for patients who may have compromised kidney function, as drugs that are predominantly renally excreted could pose risks of accumulation and toxicity in these individuals.

Nelfinavir's pharmacokinetic profile, including its metabolism and excretion route, allows for a wider therapeutic use, especially among those vulnerable due to renal issues. Understanding the elimination pathways of antiviral agents is crucial, especially in managing treatment for patients with specific comorbidities or organ system impairments. This selectivity for fecal excretion means that nelfinavir can be safely administered without concerns for accumulation that could arise with drugs that depend on renal clearance.

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