Which of the following is an example of an integrase inhibitor?

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Raltegravir is an example of an integrase inhibitor, which means it works by targeting the integrase enzyme crucial for the replication of certain viruses, particularly HIV. Integrase plays a vital role in the viral life cycle by facilitating the integration of viral DNA into the host's genomic DNA. By inhibiting this enzyme, raltegravir prevents the virus from successfully integrating its genetic material, thereby halting the replication process. This makes it an essential component of antiretroviral therapy for managing HIV infections.

Saquinavir is a protease inhibitor that interferes with the viral protease enzyme, preventing the maturation of viral proteins. Remdesivir is a nucleotide analog that inhibits RNA-dependent RNA polymerase, which is primarily used in the treatment of viral infections like COVID-19. Adefovir is a nucleotide analog that is used in the treatment of hepatitis B infections, acting as a reverse transcriptase inhibitor. Each of these agents works through different mechanisms and targets various stages of the viral life cycle, but only raltegravir specifically targets the integrase enzyme.

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